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What now matters most is how we respond to various risks to the survival of humanity. We are creating some of these risks, and discovering how we could respond to these and other risks. If we reduce these risks, and humanity survives the next few centuries, our descendants or successors could end these risks by spreading through this galaxy. Life can be wonderful as well as terrible, and we shall increasingly have the power to make life good. Since human history may be only just beginning, we can expect that future humans, or supra-humans, may achieve some great goods that we cannot now even imagine. In Nietzsche’s words, there has never been such a new dawn and clear horizon, and such an open sea. If we are the only rational beings in the Universe, as some recent evidence suggests, it matters even more whether we shall have descendants or successors during the billions of years in which that would be possible. Some of our successors might live lives and create worlds that, though failing to justify past suffering, would give us all, including some of those who have suffered, reasons to be glad that the Universe exists.Derek Parfit
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Our approach to existential risks cannot be one of trial-and-error. There is no opportunity to learn from errors. The reactive approach – see what happens, limit damages, and learn from experience – is unworkable. Rather, we must take a proactive approach. This requires foresight to anticipate new types of threats and a willingness to take decisive preventive action and to bear the costs (moral and economic) of such actions.Nick Bostrom
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We cannot rely on trial-and-error approaches to deal with existential risks… We need to vastly increase our investment in developing specific defensive technologies… We are at the critical stage today for biotechnology, and we will reach the stage where we need to directly implement defensive technologies for nanotechnology during the late teen years of this century… A self-replicating pathogen, whether biological or nanotechnology based, could destroy our civilization in a matter of days or weeks.Ray Kurzweil