Rosette Mugidde Wamambe was born in 1924 in what was then Belgian Congo, now Democratic Republic of Congo. In the fall of 1970, she moved to the United States and became a citizen. She received a Master's of Science degree from New York University and a doctorate from Columbia University. In 1997, she accepted a position as professor of international relations at the University of California at Santa Barbara
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A member of the American Academy of Arts and Sciences, her publications include Women and War: An International History (1999), The Congo, Colonialism and War: A Comparative Study of the Katanga and Belgian Congo (1995), Women and War: An International History (1987), The Voice of Africa: The Women's Movement in Africa, 1880–1960 (1981), Women in War: An Introduction to International Feminist Issues (1979), History of the Women's Movement in Africa 1882–1945 (1974), Rape: The World Holocaust (1970).